CD36 molecule
ಗೋಚರ
mammalian protein found in Homo sapiens
found in taxon
Homo sapiens[೨೦]
encoded by
CD36[೨೦]
molecular function
low-density lipoprotein particle receptor activity[೩೦][೩೧][೩೨]
determination method or standard: TAS, IMP, IEA
oxidised low-density lipoprotein particle receptor activity[೪೨]
determination method or standard: IMP
cell component
biological process
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent[೫೦]
determination method or standard: TAS
cellular response to low-density lipoprotein particle stimulus[೫೧][೩೨]
determination method or standard: ISS, IEA
positive regulation of reactive oxygen species metabolic process[೩೨]
determination method or standard: IEA
positive regulation of cytosolic calcium ion concentration[೫೧][೩೨]
determination method or standard: ISS, IEA
positive regulation of NLRP3 inflammasome complex assembly[೫೧][೩೨]
determination method or standard: ISS, IEA
positive regulation of macrophage derived foam cell differentiation[೩೧][೩೨]
determination method or standard: IEA, IMP
production of molecular mediator involved in inflammatory response[೩೮]
determination method or standard: TAS
regulation of lipopolysaccharide-mediated signaling pathway[೩೮]
determination method or standard: TAS
positive regulation of nitric oxide biosynthetic process[೬೬][೩೨]
determination method or standard: IEA, ISS
positive regulation of NF-kappaB transcription factor activity[೬೭]
determination method or standard: IGI
cellular response to oxidised low-density lipoprotein particle stimulus[೪೨]
determination method or standard: IMP
Gene Atlas image
ಕಾಮನ್ಸ್ ವರ್ಗ
Fatty taste receptors
Reference
- ↑ Ensembl Release 99, ENSP00000308165
- ↑ Ensembl Release 99, ENSP00000378268
- ↑ Ensembl Release 99, ENSP00000399421
- ↑ Ensembl Release 99, ENSP00000401863
- ↑ Ensembl Release 99, ENSP00000411411
- ↑ Ensembl Release 99, ENSP00000415743
- ↑ Ensembl Release 99, ENSP00000439543
- ↑ Ensembl Release 99, ENSP00000441956
- ↑ Ensembl Release 99, ENSP00000392298
- ↑ Ensembl Release 99, ENSP00000396258
- ↑ Ensembl Release 99, ENSP00000398760
- ↑ Ensembl Release 99, ENSP00000407690
- ↑ Ensembl Release 99, ENSP00000409762
- ↑ Ensembl Release 99, ENSP00000410371
- ↑ Ensembl Release 99, ENSP00000416388
- ↑ Ensembl Release 99, ENSP00000431296
- ↑ Ensembl Release 99, ENSP00000433659
- ↑ Ensembl Release 99, ENSP00000435698
- ↑ ೧೯.೦೦ ೧೯.೦೧ ೧೯.೦೨ ೧೯.೦೩ ೧೯.೦೪ ೧೯.೦೫ ೧೯.೦೬ ೧೯.೦೭ ೧೯.೦೮ ೧೯.೦೯ ೧೯.೧೦ ೧೯.೧೧ ೧೯.೧೨ ೧೯.೧೩ ೧೯.೧೪ ೧೯.೧೫ ೧೯.೧೬ ೧೯.೧೭ NCBI Gene, ೩೦ ಮೇ 2020, 948
- ↑ ೨೦.೦ ೨೦.೧ ೨೦.೨ ೨೦.೩ UniProt, ೧೩ ನವೆಂಬರ್ 2019, P16671
- ↑ Transporter Classification database, ೧೩ ಮಾರ್ಚ್ 2020
- ↑ Transporter Classification database, ೨೯ ಏಪ್ರಿಲ್ 2020
- ↑ OpenAlex, ೨೬ ಜನವರಿ 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
- ↑ InterPro Release 71.0, http://www.ebi.ac.uk/interpro/protein/P16671
- ↑ 9.B.39.1.4, ೨ ಅಕ್ಟೋಬರ್ 2019, hierarchical database ID heuristic
- ↑ Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting, GOA, ೮ ಏಪ್ರಿಲ್ 2019, P16671, UniProt, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671, IPI
- ↑ IntAct protein interaction database, ೮ ಏಪ್ರಿಲ್ 2019, Molecular basis of antiangiogenic thrombospondin-1 type 1 repeat domain interactions with CD36, GOA, IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ IntAct protein interaction database, ೮ ಏಪ್ರಿಲ್ 2019, CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer, GOA, IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ Critical Assessment of Protein Function Annotation, ೮ ಏಪ್ರಿಲ್ 2019, The Cysteine-Rich Interdomain Region from the Highly Variable Plasmodium falciparum Erythrocyte Membrane Protein-1 Exhibits a Conserved Structure, GOA, IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೩೦.೦ ೩೦.೧ ೩೦.೨ British Heart Foundation, ೮ ಏಪ್ರಿಲ್ 2019, PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL, GOA, TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೩೧.೦ ೩೧.೧ ೩೧.೨ ೩೧.೩ ೩೧.೪ British Heart Foundation, ೮ ಏಪ್ರಿಲ್ 2019, Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species, GOA, IMP, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೩೨.೦೦ ೩೨.೦೧ ೩೨.೦೨ ೩೨.೦೩ ೩೨.೦೪ ೩೨.೦೫ ೩೨.೦೬ ೩೨.೦೭ ೩೨.೦೮ ೩೨.೦೯ ೩೨.೧೦ ೩೨.೧೧ ೩೨.೧೨ ೩೨.೧೩ ೩೨.೧೪ ೩೨.೧೫ ೩೨.೧೬ ೩೨.೧೭ ೩೨.೧೮ ೩೨.೧೯ ೩೨.೨೦ ೩೨.೨೧ ೩೨.೨೨ ೩೨.೨೩ ೩೨.೨೪ ೩೨.೨೫ ೩೨.೨೬ ೩೨.೨೭ ೩೨.೨೮ ೩೨.೨೯ ೩೨.೩೦ ೩೨.೩೧ ೩೨.೩೨ ೩೨.೩೩ ೩೨.೩೪ ೩೨.೩೫ ೩೨.೩೬ ೩೨.೩೭ ೩೨.೩೮ ೩೨.೩೯ ೩೨.೪೦ ೩೨.೪೧ ೩೨.೪೨ ೩೨.೪೩ ೩೨.೪೪ ೩೨.೪೫ ೩೨.೪೬ ೩೨.೪೭ ೩೨.೪೮ ೩೨.೪೯ ೩೨.೫೦ ೩೨.೫೧ ೩೨.೫೨ ೩೨.೫೩ ೩೨.೫೪ ೩೨.೫೫ ೩೨.೫೬ ೩೨.೫೭ ೩೨.೫೮ ೩೨.೫೯ ೩೨.೬೦ ೩೨.೬೧ ೩೨.೬೨ ೩೨.೬೩ ೩೨.೬೪ Ensembl genome database project, ೮ ಏಪ್ರಿಲ್ 2019, GOA, IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೩೩.೦ ೩೩.೧ ೩೩.೨ British Heart Foundation, ೮ ಏಪ್ರಿಲ್ 2019, GOA, ISS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL, GOA, ೮ ಏಪ್ರಿಲ್ 2019, P16671, UniProt, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671, IDA
- ↑ ೩೫.೦ ೩೫.೧ ೩೫.೨ British Heart Foundation, ೮ ಏಪ್ರಿಲ್ 2019, Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species, GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ARUK-UCL, ೧ ಜನವರಿ 2018, CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer, GOA, TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P16671&geneProductId=UniProtKB:P16671
- ↑ ARUK-UCL, ೧ ಜನವರಿ 2018, CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer, GOA, IC, http://www.ebi.ac.uk/QuickGO/annotations?protein=P16671&geneProductId=UniProtKB:P16671
- ↑ ೩೮.೦ ೩೮.೧ ೩೮.೨ ೩೮.೩ ೩೮.೪ ೩೮.೫ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, CD36 Deficiency Suppresses Epileptic Seizures, GOA, TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid, GOA, TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೪೦.೦ ೪೦.೧ ೪೦.೨ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia., GOA, IMP, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೪೧.೦ ೪೧.೧ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer, GOA, IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೪೨.೦ ೪೨.೧ ೪೨.೨ ೪೨.೩ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, Oxidized Lipoprotein Uptake Through the CD36 Receptor Activates the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells., GOA, IMP, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer, GOA, TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function., GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer, GOA, IC, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function., GOA, IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೪೭.೦ ೪೭.೧ ೪೭.೨ ೪೭.೩ ೪೭.೪ ೪೭.೫ ೪೭.೬ GOA, ೮ ಏಪ್ರಿಲ್ 2019, P16671, UniProt, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671, IEA
- ↑ ೪೮.೦ ೪೮.೧ ೪೮.೨ Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting, GOA, ೮ ಏಪ್ರಿಲ್ 2019, P16671, UniProt, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671, IDA
- ↑ Human Protein Atlas, ೮ ಏಪ್ರಿಲ್ 2019, GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೫೦.೦೦ ೫೦.೦೧ ೫೦.೦೨ ೫೦.೦೩ ೫೦.೦೪ ೫೦.೦೫ ೫೦.೦೬ ೫೦.೦೭ ೫೦.೦೮ ೫೦.೦೯ ೫೦.೧೦ ೫೦.೧೧ ೫೦.೧೨ ೫೦.೧೩ Reactome, ೮ ಏಪ್ರಿಲ್ 2019, GOA, TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೫೧.೦೦ ೫೧.೦೧ ೫೧.೦೨ ೫೧.೦೩ ೫೧.೦೪ ೫೧.೦೫ ೫೧.೦೬ ೫೧.೦೭ ೫೧.೦೮ ೫೧.೦೯ ೫೧.೧೦ ೫೧.೧೧ ೫೧.೧೨ ೫೧.೧೩ ೫೧.೧೪ ೫೧.೧೫ GOA, ೮ ಏಪ್ರಿಲ್ 2019, P16671, UniProt, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671, ISS
- ↑ ೫೨.೦ ೫೨.೧ Proteome Inc., ೮ ಏಪ್ರಿಲ್ 2019, Isolation and characterization of platelet glycoprotein IV (CD36), GOA, TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೫೩.೦ ೫೩.೧ ೫೩.೨ InterPro, ೮ ಏಪ್ರಿಲ್ 2019, GOA, IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ British Heart Foundation, ೨೩ ಮೇ 2017, GOA, ISS, http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P16671
- ↑ British Heart Foundation, ೨೩ ಮೇ 2017, Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species, GOA, IDA, http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P16671
- ↑ ೫೬.೦ ೫೬.೧ Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells, GOA, ೮ ಏಪ್ರಿಲ್ 2019, P16671, UniProt, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671, IDA
- ↑ Human colostrum: identification of minor proteins in the aqueous phase by proteomics, GOA, ೨೩ ಮೇ 2017, P16671, UniProt, http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P16671, IDA
- ↑ Human colostrum: identification of minor proteins in the aqueous phase by proteomics, GOA, ೮ ಏಪ್ರಿಲ್ 2019, P16671, UniProt, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671, HDA
- ↑ ARUK-UCL, ೧ ಜನವರಿ 2018, CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer, GOA, IPI, http://www.ebi.ac.uk/QuickGO/annotations?protein=P16671&geneProductId=UniProtKB:P16671
- ↑ ೬೦.೦ ೬೦.೧ ೬೦.೨ ೬೦.೩ British Heart Foundation, ೮ ಏಪ್ರಿಲ್ 2019, Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake, GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೬೧.೦ ೬೧.೧ British Heart Foundation, ೮ ಏಪ್ರಿಲ್ 2019, Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages, GOA, ISS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೬೨.೦ ೬೨.೧ Proteome Inc., ೮ ಏಪ್ರಿಲ್ 2019, Identification of glycoprotein IV (CD36) as a primary receptor for platelet-collagen adhesion, GOA, TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ GOA, ೨೩ ಮೇ 2017, P16671, UniProt, http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P16671, IEA
- ↑ Reactome, ೨೩ ಮೇ 2017, GOA, TAS, http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P16671
- ↑ Proteome Inc., ೮ ಏಪ್ರಿಲ್ 2019, Structural organization of the gene for human CD36 glycoprotein, GOA, NAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೬೬.೦ ೬೬.೧ ೬೬.೨ ೬೬.೩ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, GOA, ISS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ೬೭.೦ ೬೭.೧ ೬೭.೨ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer, GOA, IGI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ ARUK-UCL, ೮ ಏಪ್ರಿಲ್ 2019, CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer, GOA, IMP, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671
- ↑ YuBioLab, ೮ ಏಪ್ರಿಲ್ 2019, CD36 is indispensable for thermogenesis under conditions of fasting and cold stress., GOA, ISS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16671