ವಿಷಯಕ್ಕೆ ಹೋಗು

Interleukin 6

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mammalian protein found in Homo sapiens

ಉದಾಹರಣೆಗೆ

ಇದರ ಭಾಗವಾಗಿದೆ

interleukin-6[೧೩]
four-helical cytokine-like, core[೧೩]
Interleukin-6/GCSF/MGF, conserved site, protein family[೧೪]

found in taxon

Homo sapiens[೧೧]

encoded by

molecular function

cytokine activity[೧೫][೧೬][೧೭][೧೮][೧೯][೨೦]

determination method: NAS, IDA, ISS, IEA

growth factor activity[೨೧][೧೭][೨೨][೨೩]

determination method: IDA, IEA, TAS

interleukin-6 receptor binding[೨೪][೨೫][೨೬][೧೮]

determination method: NAS, IEA, TAS, IPI

protein binding[೨೭][೨೮][೨೯][೩೦][೩೧]

determination method: IPI

cell component

extracellular region[೩೨][೧೭][೧೮]

determination method: IEA, TAS

interleukin-6 receptor complex[೨೨][೩೩]

determination method: IDA

extracellular space[೧೭][೩೪][೩೫][೨೦]

determination method: IDA, IEA

endoplasmic reticulum lumen[೩೨]

determination method: TAS

biological process

regulation of angiogenesis[೩೬]

determination method: IC

positive regulation of translation[೩೭]

determination method: IDA

platelet activation[೩೮]

determination method: TAS

humoral immune response[೩೯]

determination method: IC

defense response to virus[೨೦]

determination method: IDA

response to peptidoglycan[೪೦]

determination method: NAS

neuron projection development[೪೧]

determination method: IMP

defense response to Gram-positive bacterium[೪೨]

determination method: TAS

negative regulation of fat cell differentiation[೪೩]

determination method: NAS

positive regulation of peptidyl-serine phosphorylation[೪೪]

determination method: IDA

positive regulation of leukocyte chemotaxis[೪೨]

determination method: TAS

positive regulation of T cell proliferation[೪೫]

determination method: IDA

positive regulation of interleukin-6 production[೪೬]

determination method: IDA

positive regulation of peptidyl-tyrosine phosphorylation[೪೪]

determination method: IDA

positive regulation of acute inflammatory response[೪೭]

determination method: IDA

inflammatory response[೩೫]

determination method: IDA

negative regulation of collagen biosynthetic process[೪೮]

determination method: IDA

positive regulation of MAPK cascade[೪೪][೪೮]

determination method: IDA

hepatic immune response[೪೯][೪೭]

determination method: IDA, TAS

monocyte chemotaxis[೫೦]

determination method: IC

positive regulation of DNA-binding transcription factor activity[೫೧]

determination method: IDA

negative regulation of apoptotic process[೫೨]

determination method: IDA

positive regulation of osteoblast differentiation[೫೩]

determination method: TAS

positive regulation of NF-kappaB transcription factor activity[೪೮]

determination method: IDA

acute-phase response[೪೯][೧೭]

determination method: IEA, TAS

immune response[೧೮]

determination method: IEA

regulation of vascular endothelial growth factor production[೫೪]

determination method: IDA

positive regulation of chemokine production[೪೦][೪೬]

determination method: NAS, IDA

negative regulation of lipid storage[೪೩]

determination method: NAS

neutrophil mediated immunity[೪೨]

determination method: TAS

positive regulation of smooth muscle cell proliferation[೪೬]

determination method: IDA

positive regulation of type B pancreatic cell apoptotic process[೫೫]

determination method: TAS

response to glucocorticoid[೩೫]

determination method: IDA

defense response to Gram-negative bacterium[೪೨]

determination method: TAS

positive regulation of cell population proliferation[೫೬][೨೨]

determination method: IDA, IMP

positive regulation of apoptotic process[೫೭]

determination method: IDA

positive regulation of B cell activation[೧೯]

determination method: IDA

post-translational protein modification[೩೨]

determination method: TAS

regulation of signaling receptor activity[೫೮]

determination method: IEA

positive regulation of tyrosine phosphorylation of STAT protein[೨೩][೫೯]

determination method: IDA

neutrophil apoptotic process[೫೨]

determination method: IDA

negative regulation of cell population proliferation[೬೦]

determination method: TAS

positive regulation of gene expression[೫೯]

determination method: IDA

endocrine pancreas development[೧೬]

determination method: ISS

negative regulation of bone resorption[೧೬]

determination method: ISS

positive regulation of transcription, DNA-templated[೬೧][೬೨][೫೧]

determination method: IDA, IMP

positive regulation of transcription by RNA polymerase II[೧೬][೪೪][೬೩][೬೪]

determination method: IDA, ISS

glucagon secretion[೧೬]

determination method: ISS

cellular response to hydrogen peroxide[೬೫]

determination method: IDA

cellular response to lipopolysaccharide[೬೬]

determination method: IMP

T-helper 17 cell lineage commitment[೬೭]

determination method: ISS

positive regulation of T-helper 2 cell cytokine production[೧೬]

determination method: ISS

negative regulation of interleukin-1-mediated signaling pathway[೧೬]

determination method: ISS

cytokine-mediated signaling pathway[೩೨][೨೨][೨೩]

determination method: IDA, TAS

interleukin-6-mediated signaling pathway[೩೨][೬೩][೬೮]

determination method: IDA, TAS

positive regulation of receptor signaling pathway via JAK-STAT[೬೪][೪೮][೬೮][೬೯]

determination method: IC, IDA

ಭಾಗವನ್ನು ಹೊಂದಿದೆ

Interleukin-6/GCSF/MGF, conserved site[೧೩]

Reference

  1. Freebase Data Dumps, ೨೮ ಅಕ್ಟೋಬರ್ 2013
  2. ೨.೦ ೨.೧ ೨.೨ ೨.೩ ೨.೪ NCBI Gene, ೩೦ ಮೇ 2020, 3569
  3. ೩.೦೦ ೩.೦೧ ೩.೦೨ ೩.೦೩ ೩.೦೪ ೩.೦೫ ೩.೦೬ ೩.೦೭ ೩.೦೮ ೩.೦೯ P05231, ೯ ಆಗಸ್ಟ್ 2016, UniProt, ಆಂಗ್ಲ
  4. Ensembl Release 99, ENSP00000385675
  5. Ensembl Release 99, ENSP00000258743
  6. Ensembl Release 99, ENSP00000384928
  7. Ensembl Release 99, ENSP00000385043
  8. Ensembl Release 99, ENSP00000385227
  9. Ensembl Release 99, ENSP00000385718
  10. Ensembl Release 99, ENSP00000405150
  11. ೧೧.೦ ೧೧.೧ ೧೧.೨ ೧೧.೩ UniProt, ೧೩ ನವೆಂಬರ್ 2019, P05231
  12. OpenAlex, ೨೬ ಜನವರಿ 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
  13. ೧೩.೦ ೧೩.೧ ೧೩.೨ InterPro Release 71.0, http://www.ebi.ac.uk/interpro/protein/P05231
  14. inferred from protein domain or family
  15. NAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Tumor necrosis factor alpha decreases, and interleukin-10 increases, the sensitivity of human monocytes to dexamethasone: potential regulation of the glucocorticoid receptor, GOA
  16. ೧೬.೦ ೧೬.೧ ೧೬.೨ ೧೬.೩ ೧೬.೪ ೧೬.೫ ೧೬.೬ ISS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, GOA
  17. ೧೭.೦ ೧೭.೧ ೧೭.೨ ೧೭.೩ ೧೭.೪ IEA, ೨೭ ಮಾರ್ಚ್ 2018, P05231, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, UniProt
  18. ೧೮.೦ ೧೮.೧ ೧೮.೨ ೧೮.೩ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, InterPro, GOA
  19. ೧೯.೦ ೧೯.೧ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin, GOA
  20. ೨೦.೦ ೨೦.೧ ೨೦.೨ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines, GOA
  21. TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, Proteome Inc., Monocyte-derived human B-cell growth factor identified as interferon-beta 2 (BSF-2, IL-6), GOA
  22. ೨೨.೦ ೨೨.೧ ೨೨.೨ ೨೨.೩ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Molecular cloning and expression of an IL-6 signal transducer, gp130, GOA
  23. ೨೩.೦ ೨೩.೧ ೨೩.೨ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Signaling of human ciliary neurotrophic factor (CNTF) revisited. The interleukin-6 receptor can serve as an alpha-receptor for CTNF, GOA
  24. TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, Proteome Inc., Loss of IL-6 receptor expression in cervical carcinoma cells inhibits autocrine IL-6 stimulation: abrogation of constitutive monocyte chemoattractant protein-1 production, GOA
  25. NAS, ೨೭ ಮಾರ್ಚ್ 2018, P05231, Marked cell-type-specific differences in glycosylation of human interleukin-6, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, UniProt
  26. IPI, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex, GOA
  27. IPI, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, IntAct protein interaction database, Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network, GOA
  28. IPI, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, IntAct protein interaction database, Detection of direct binding of human herpesvirus 8-encoded interleukin-6 (vIL-6) to both gp130 and IL-6 receptor (IL-6R) and identification of amino acid residues of vIL-6 important for IL-6R-dependent and -independent signaling, GOA
  29. IPI, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, IntAct protein interaction database, A human protein-protein interaction network: a resource for annotating the proteome, GOA
  30. IPI, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, IntAct protein interaction database, Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex, GOA
  31. IPI, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, IntAct protein interaction database, Structural Organization of a Full-Length gp130/LIF-R Cytokine Receptor Transmembrane Complex, GOA
  32. ೩೨.೦ ೩೨.೧ ೩೨.೨ ೩೨.೩ ೩೨.೪ TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, Reactome, GOA
  33. IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex, GOA
  34. IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Bacterial induction of TNF-alpha converting enzyme expression and IL-6 receptor alpha shedding regulates airway inflammatory signaling, GOA
  35. ೩೫.೦ ೩೫.೧ ೩೫.೨ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Tumor necrosis factor alpha decreases, and interleukin-10 increases, the sensitivity of human monocytes to dexamethasone: potential regulation of the glucocorticoid receptor, GOA
  36. IC, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Interleukin 6 induces the expression of vascular endothelial growth factor, GOA
  37. IDA, ೨೭ ಮಾರ್ಚ್ 2018, P05231, BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, UniProt
  38. TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Platelet activation induced by interleukin-6: evidence for a mechanism involving arachidonic acid metabolism, GOA
  39. IC, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin, GOA
  40. ೪೦.೦ ೪೦.೧ NAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Bacterial induction of TNF-alpha converting enzyme expression and IL-6 receptor alpha shedding regulates airway inflammatory signaling, GOA
  41. IMP, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6, GOA
  42. ೪೨.೦ ೪೨.೧ ೪೨.೨ ೪೨.೩ TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Bacterial induction of TNF-alpha converting enzyme expression and IL-6 receptor alpha shedding regulates airway inflammatory signaling, GOA
  43. ೪೩.೦ ೪೩.೧ NAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes, GOA
  44. ೪೪.೦ ೪೪.೧ ೪೪.೨ ೪೪.೩ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, Mouse Genome Informatics, Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells, GOA
  45. IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Synergistic activation of human T cells by interleukin 1 and interleukin 6, GOA
  46. ೪೬.೦ ೪೬.೧ ೪೬.೨ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Novel path to activation of vascular smooth muscle cells: up-regulation of gp130 creates an autocrine activation loop by IL-6 and its soluble receptor, GOA
  47. ೪೭.೦ ೪೭.೧ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells, GOA
  48. ೪೮.೦ ೪೮.೧ ೪೮.೨ ೪೮.೩ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, JAK/STAT but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of Type II collagen, aggrecan core, and link protein transcription in articular chondrocytes. Association with a down-regulation of SOX9 expression, GOA
  49. ೪೯.೦ ೪೯.೧ TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE), GOA
  50. IC, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Novel path to activation of vascular smooth muscle cells: up-regulation of gp130 creates an autocrine activation loop by IL-6 and its soluble receptor, GOA
  51. ೫೧.೦ ೫೧.೧ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells, GOA
  52. ೫೨.೦ ೫೨.೧ IDA, ೨೭ ಮಾರ್ಚ್ 2018, P05231, Interleukin-6 suppression of neutrophil apoptosis is neutrophil concentration dependent, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, UniProt
  53. TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells, GOA
  54. IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Interleukin 6 induces the expression of vascular endothelial growth factor, GOA
  55. TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Interleukin-6 regulates pancreatic alpha-cell mass expansion, GOA
  56. IMP, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Interleukin-6 regulates pancreatic alpha-cell mass expansion, GOA
  57. IDA, ೨೭ ಮಾರ್ಚ್ 2018, P05231, Both Stat3-activation and Stat3-independent BCL2 downregulation are important for interleukin-6-induced apoptosis of 1A9-M cells, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, UniProt
  58. IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, Gene Ontology Consortium, GOA
  59. ೫೯.೦ ೫೯.೧ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Interleukin-6 modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway, GOA
  60. TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, Proteome Inc., Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines, GOA
  61. IMP, ೨೭ ಮಾರ್ಚ್ 2018, P05231, Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, UniProt
  62. IDA, ೨೭ ಮಾರ್ಚ್ 2018, P05231, B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, UniProt
  63. ೬೩.೦ ೬೩.೧ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation, GOA
  64. ೬೪.೦ ೬೪.೧ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Interleukin-6 transcriptionally regulates prohibitin expression in intestinal epithelial cells, GOA
  65. IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, IL-6 protects against hyperoxia-induced mitochondrial damage via Bcl-2-induced Bak interactions with mitofusins, GOA
  66. IMP, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, Mouse Genome Informatics, SASH1 is a scaffold molecule in endothelial TLR4 signaling, GOA
  67. ISS, ೨೭ ಮಾರ್ಚ್ 2018, P05231, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, UniProt
  68. ೬೮.೦ ೬೮.೧ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2, GOA
  69. IC, http://www.ebi.ac.uk/QuickGO/annotations?protein=P05231&geneProductId=UniProtKB:P05231, ೨೭ ಮಾರ್ಚ್ 2018, British Heart Foundation, Interleukin-6 transcriptionally regulates prohibitin expression in intestinal epithelial cells, GOA
  70. Identifiers.org
"https://kn.wikipedia.org/wiki/ವಿಶೇಷ:AboutTopic/Q412889" ಇಂದ ಪಡೆಯಲ್ಪಟ್ಟಿದೆ