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Glycoprotein hormones, alpha polypeptide

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mammalian protein found in Homo sapiens

External resources

UMLS CUI
C0017963[೧]
PDB structure ID
1DZ7[೨]
1E9J[೨]
1FL7[೨]
1HCN[೨]
1HD4[೨]
1HRP[೨]
1QFW[೨]
1XWD[೨]
4AY9[೨]
4MQW[೨]
Ensembl protein ID
ENSP00000486024[೩]
ENSP00000358595[೪]
ENSP00000482232[೫]
ENSP00000486666[೬]
ENSP00000487300[೭]
RefSeq protein ID
NP_000726[೮]
NP_001239312[೮]
UniProt protein ID
P01215[೯]
Microsoft Academic ID
2780181328
Freebase ಐಡಿ
/m/03d996t

ಉದಾಹರಣೆಗೆ

ಪ್ರೋಟೀನ್[೯]

ಇದರ ಭಾಗವಾಗಿದೆ

Cystine-knot cytokine[೧೦]
glycoprotein hormone alpha chain[೧೦]

found in taxon

Homo sapiens[೯]

encoded by

CGA[೯]

molecular function

protein binding[೧೧][೧೨][೧೩]

determination method: IPI

hormone activity[೧೪][೧೫][೧೬][೧೭]

determination method: IEA, IMP, TAS

hormone activity[೧೮][೧೯][೨೦]

determination method: IEA, IMP

follicle-stimulating hormone activity[೨೧][೨೨]

determination method: IDA

follicle-stimulating hormone activity[೨೩][೨೪][೨೫]

determination method: IBA, IDA

cell component

Golgi lumen[೨೬]

determination method: TAS

extracellular region[೨೬][೧೯][೨೦]

determination method: IEA, TAS

extracellular space[೨೧][೨೨]

determination method: IDA

follicle-stimulating hormone complex[೨೧][೨೨]

determination method: IDA

extracellular space[೨೩][೨೪][೨೫]

determination method: IBA, IDA

follicle-stimulating hormone complex[೨೩][೨೪][೨೫]

determination method: IBA, IDA

biological process

cell-cell signaling[೧೪]

determination method: TAS

peptide hormone processing[೨೬]

determination method: TAS

positive regulation of cell population proliferation[೨೭]

determination method: NAS

positive regulation of transcription by RNA polymerase II[೨೭]

determination method: NAS

signal transduction[೧೪]

determination method: TAS

positive regulation of cell migration[೨೭]

determination method: NAS

regulation of transcription by RNA polymerase II[೨೬]

determination method: TAS

regulation of signaling receptor activity[೨೮]

determination method: IEA

G protein-coupled receptor signaling pathway[೨೯]

determination method: TAS

G protein-coupled receptor signaling pathway[೨೬][೨೪]

determination method: IDA, TAS

regulation of signaling receptor activity[೨೪]

determination method: IDA

positive regulation of steroid biosynthetic process[೨೧]

determination method: IDA

thyroid hormone generation[೨೫]

determination method: IBA

positive regulation of steroid biosynthetic process[೨೩][೨೫]

determination method: IBA, IDA

Reference

  1. ↑ UMLS 2023, ೨೪ ಮೇ 2023, inferred by common MeSH mappings on source and on Wikidata
  2. ↑ ೨.೦೦ ೨.೦೧ ೨.೦೨ ೨.೦೩ ೨.೦೪ ೨.೦೫ ೨.೦೬ ೨.೦೭ ೨.೦೮ ೨.೦೯ P01215, ೯ ಆಗಸ್ಟ್ 2016, UniProt, ಆಂಗ್ಲ
  3. ↑ Ensembl Release 99, ENSP00000486024
  4. ↑ Ensembl Release 99, ENSP00000358595
  5. ↑ Ensembl Release 99, ENSP00000482232
  6. ↑ Ensembl Release 99, ENSP00000486666
  7. ↑ Ensembl Release 99, ENSP00000487300
  8. ↑ ೮.೦ ೮.೧ NCBI Gene, ೩೦ ಮೇ 2020, 1081
  9. ↑ ೯.೦ ೯.೧ ೯.೨ ೯.೩ UniProt, ೧೩ ನವೆಂಬರ್ 2019, P01215
  10. ↑ ೧೦.೦ ೧೦.೧ InterPro Release 71.0, http://www.ebi.ac.uk/interpro/protein/P01215
  11. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, ೮ ಏಪ್ರಿಲ್ 2019, IntAct protein interaction database, Structure of human follicle-stimulating hormone in complex with its receptor, GOA
  12. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, ೮ ಏಪ್ರಿಲ್ 2019, IntAct protein interaction database, Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor, GOA
  13. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, ೮ ಏಪ್ರಿಲ್ 2019, IntAct protein interaction database, Three-dimensional structure of human follicle-stimulating hormone, GOA
  14. ↑ ೧೪.೦ ೧೪.೧ ೧೪.೨ TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, ೩೧ ಅಕ್ಟೋಬರ್ 2017, Proteome Inc., Isolation, cloning and sequence analysis of the cDNA for the α-subunit of human chorionic gonadotropin, GOA
  15. ↑ IMP, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, ೩೧ ಅಕ್ಟೋಬರ್ 2017, AgBase, Molecular biology of channel catfish gonadotropin receptors: 1. Cloning of a functional luteinizing hormone receptor and preovulatory induction of gene expression, GOA
  16. ↑ IEA, ೩೧ ಅಕ್ಟೋಬರ್ 2017, P01215, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, UniProt
  17. ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, ೩೧ ಅಕ್ಟೋಬರ್ 2017, InterPro, GOA
  18. ↑ IMP, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, ೮ ಏಪ್ರಿಲ್ 2019, AgBase, Molecular biology of channel catfish gonadotropin receptors: 1. Cloning of a functional luteinizing hormone receptor and preovulatory induction of gene expression, GOA
  19. ↑ ೧೯.೦ ೧೯.೧ IEA, ೮ ಏಪ್ರಿಲ್ 2019, P01215, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, UniProt
  20. ↑ ೨೦.೦ ೨೦.೧ IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, ೮ ಏಪ್ರಿಲ್ 2019, InterPro, GOA
  21. ↑ ೨೧.೦ ೨೧.೧ ೨೧.೨ ೨೧.೩ IDA, ೧ ಜನವರಿ 2018, P01215, Expression of biologically active human follitropin in Chinese hamster ovary cells, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, UniProt
  22. ↑ ೨೨.೦ ೨೨.೧ ೨೨.೨ IDA, ೧ ಜನವರಿ 2018, P01215, Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, UniProt
  23. ↑ ೨೩.೦ ೨೩.೧ ೨೩.೨ ೨೩.೩ IDA, ೮ ಏಪ್ರಿಲ್ 2019, P01215, Expression of biologically active human follitropin in Chinese hamster ovary cells, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, UniProt
  24. ↑ ೨೪.೦ ೨೪.೧ ೨೪.೨ ೨೪.೩ ೨೪.೪ IDA, ೮ ಏಪ್ರಿಲ್ 2019, P01215, Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, UniProt
  25. ↑ ೨೫.೦ ೨೫.೧ ೨೫.೨ ೨೫.೩ ೨೫.೪ IBA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, ೮ ಏಪ್ರಿಲ್ 2019, GO Central, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA
  26. ↑ ೨೬.೦ ೨೬.೧ ೨೬.೨ ೨೬.೩ ೨೬.೪ TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, ೮ ಏಪ್ರಿಲ್ 2019, Reactome, GOA
  27. ↑ ೨೭.೦ ೨೭.೧ ೨೭.೨ NAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01215, ೮ ಏಪ್ರಿಲ್ 2019, British Heart Foundation, Follicular stimulating hormone enhances Notch 1 expression in SK-OV-3 ovarian cancer cells, GOA
  28. ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, ೩೧ ಅಕ್ಟೋಬರ್ 2017, Gene Ontology Consortium, GOA
  29. ↑ TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01215&geneProductId=UniProtKB:P01215, ೩೧ ಅಕ್ಟೋಬರ್ 2017, Reactome, GOA
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