valproic acid

ಉದಾಹರಣೆಗೆ

type of chemical entity

ಉಪವರ್ಗ

branched chain fatty acids

ಉಪಕ್ರಮ

1967^[೩೦]

chemical structure

mass

೧೪೪.೧೧೫ dalton^[೩೧]

significant event

Dépakine case

conjugate base

valproate

chemical formula

C₈H₁₆O₂^[೧೨]

canonical SMILES

CCCC(CCC)C(=O)O^[೧೨]

World Health Organisation international non-proprietary name

valproic acid^{[೧೬][೩೨]}

found in taxon

Valeriana officinalis^[೩೩]

medical condition treated

ದ್ವಿಧ್ರುವಿ ಅಸ್ವಸ್ಥತೆ^[೩೪]

early-onset Alzheimer's disease^[೩೪]

childhood absence epilepsy^[೩೪]

complex partial seizure^[೩೪]

physically interacts with

histone deacetylase 1^[೩೫]

subject has role: enzyme inhibitor

Aldehyde dehydrogenase 5 family member A1^[೩೬]

subject has role: reaction inhibitor

legal status (medicine)

boxed warning^[೩೭]

pregnancy category

Australian pregnancy category D

US pregnancy category X

subject has role

enzyme inhibitor^[೩೮]

anticonvulsant agent^[೩೮]

GABA agents^[೩೮]

antimanic agents^[೩೮]

essential medicine

developmental toxicant^[೩೯]

ಆರಂಭದ ಸಮಯ: ೧ ಜುಲೈ 1987

different from

valproate

sodium valproate

valproate calcium

ಕಾಮನ್ಸ್ ವರ್ಗ

Valproic acid

Reference

1. ↑ ^{೧.೦ ೧.೧} ChEMBL, ೧೯ ನವೆಂಬರ್ 2016, ಆಂಗ್ಲ, VALPROIC ACID, CHEMBL109
2. ↑ IUPHAR/BPS Guide to PHARMACOLOGY, ೧೯ ನವೆಂಬರ್ 2016, ಆಂಗ್ಲ, 7009, valproic acid
3. ↑ ECHA Substance Infocard database, ೨೭ ಡಿಸೆಂಬರ್ 2018, 100.002.525, 2-propylvaleric acid, CAS no.: 99-66-1
4. ↑ Protein Data Bank, ೧೯ ಅಕ್ಟೋಬರ್ 2016, ಆಂಗ್ಲ, 1DIT, 1DIT
5. ↑ ^{೫.೦ ೫.೧} UniChem
6. ↑ ^{೬.೦ ೬.೧ ೬.೨ ೬.೩ ೬.೪ ೬.೫} Global Substance Registration System, ೧೯ ನವೆಂಬರ್ 2016, ಆಂಗ್ಲ, valproic acid, 614OI1Z5WI
7. ↑ N0000020512, ೨೬ ಫೆಬ್ರವರಿ 2018, NDF-RT
8. ↑ Freebase Data Dumps, ೨೮ ಅಕ್ಟೋಬರ್ 2013
9. ↑ California Proposition 65 list of chemicals, ೭ ಜನವರಿ 2020, https://oehha.ca.gov/chemicals/valproate
10. ↑ ChEBI, ೧೯ ಅಕ್ಟೋಬರ್ 2016, ಆಂಗ್ಲ, valproic acid, 39867
11. ↑ ^{೧೧.೦ ೧೧.೧} Nuovo soggettario, https://thes.bncf.firenze.sbn.it/termine.php?id=52464, ೧೭ ಜೂನ್ 2021
12. ↑ ^{೧೨.೦ ೧೨.೧ ೧೨.೨ ೧೨.೩ ೧೨.೪} PubChem, ೧೯ ನವೆಂಬರ್ 2016, ಆಂಗ್ಲ, 3121, VALPROIC ACID
13. ↑ ^{೧೩.೦ ೧೩.೧ ೧೩.೨ ೧೩.೩ ೧೩.೪ ೧೩.೫ ೧೩.೬} NIJJYAXOARWZEE-UHFFFAOYSA-N, InChIKey
14. ↑ Quora
15. ↑ YSO-Wikidata mapping project, ೯ ಫೆಬ್ರವರಿ 2022
16. ↑ ^{೧೬.೦ ೧೬.೧} ChEMBL, ೧೯ ಜನವರಿ 2016, ಆಂಗ್ಲ, Valproic Acid, CHEMBL109
17. ↑ ^{೧೭.೦ ೧೭.೧} OpenAlex, ೨೬ ಜನವರಿ 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
18. ↑ ChEBI release 2020-09-01
19. ↑ CAS Common Chemistry, ೯ ಏಪ್ರಿಲ್ 2021, NIJJYAXOARWZEE-UHFFFAOYSA-N, https://commonchemistry.cas.org/detail?cas_rn=99-66-1
20. ↑ International Chemical Identifier, InChI=1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
21. ↑ CosIng database, ೨೮ ಡಿಸೆಂಬರ್ 2019, 94126, VALPROIC ACID, CAS no.: 99-66-1
22. ↑ DrugBank, ಆಂಗ್ಲ, ೧೭ ನವೆಂಬರ್ 2015, 00313, Valproic Acid
23. ↑ ^{೨೩.೦ ೨೩.೧} inferred from InChIKey
24. ↑ Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard
25. ↑ ChemSpider, ೧೯ ನವೆಂಬರ್ 2016, ಆಂಗ್ಲ, 3009, Valproic acid
26. ↑ National Central Library of Florence
27. ↑ ನ್ಯಾಷನಲ್ ಲೈಬ್ರರಿ ಇಸ್ರೇಲ್
28. ↑ https://mednet-communities.net/inn/db/ViewINN.aspx?i=3300
29. ↑ Hazardous Substances Data Bank, ೧೦ ಮೇ 2021, ೨೮ ಅಕ್ಟೋಬರ್ 2019, VALPROIC ACID, 3582
30. ↑ https://www.aljazeera.com/economy/2020/8/3/frances-sanofi-charged-with-manslaughter-in-birth-defects-case
31. ↑ PubChem, ೧೯ ಅಕ್ಟೋಬರ್ 2016, ಆಂಗ್ಲ, 3121, VALPROIC ACID
32. ↑ Recommended INN: List 13, 1973
33. ↑ Alkaloid-Bearing Plants and Their Contained Alkaloids. 1957-1968
34. ↑ ^{೩೪.೦ ೩೪.೧ ೩೪.೨ ೩೪.೩} N0000147028, ೧೩ ಡಿಸೆಂಬರ್ 2016, NDF-RT, ಆಂಗ್ಲ
35. ↑ IUPHAR/BPS Guide to PHARMACOLOGY, ೧೭ ಆಗಸ್ಟ್ 2016, 7009, ಆಂಗ್ಲ
36. ↑ Open Targets Platform, ೧೪ ಆಗಸ್ಟ್ 2023, https://platform.opentargets.org/drug/CHEMBL109
37. ↑ FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links., https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
38. ↑ ^{೩೮.೦ ೩೮.೧ ೩೮.೨ ೩೮.೩} Medical Subject Headings, ೧೫ ಮಾರ್ಚ್ 2018, D014635
39. ↑ California Proposition 65 list of chemicals, ೧೯ ಮಾರ್ಚ್ 2020, https://oehha.ca.gov/chemicals/valproate